The St. Louis Cardinals take a .500 record (3-3) into their third series of the year against Milwaukee. The Brewers come to town with a record of 2-4. Garrett Stephenson (0-1) gets his second start for the Cardinals. Ruben Quevedo (0-1) pitches for Milwaukee. The Royals (2-3) play their first road game of the year, as they start a series at Fenway Park in Boston. Kansas City sends Dan Reichert (0-1) to the mound against Red Sox knuckleballer Tim Wakefield (0-0). Reichert pitched well in his first start, despite taking the loss.

Missourinet