Marcell Ozuna hit a three-run homer to back six solid innings from Adam Wainwright as the Cardinals beat the Brewers 5-2 in St. Louis.
Wainwright gave up one run on four hits as he evened his record at 2-2.
Jordan Hicks recorded the final out for his seventh save.
Yadier Molina added a solo homer for the Redbirds, who swept the three-game series and have won five straight overall.
Eric Thames went deep and scored both runs for the Crew, who have dropped four in-a-row and seven of their last eight. Jhoulys Chacin allowed four runs in as many innings to suffer the loss.