Home runs from Yadier Molina and Dexter Fowler propelled the St. Louis Cardinals past the Cincinnati Reds 5-3 at Great American Ball Park.
Molina drove in three, while Luke Weaver came away with the win.
Weaver improved to 2-0, striking out seven over six innings of two-run ball. Bud Norris nailed down his second save.
Devin Mesoraco hit a two-run shot off Weaver for Cincinnati, which has lost the first two of the four-game series and six straight overall.