Colby Rasmus homered in the second inning and Carlos Gomez followed with a solo shot in the fourth off Yankees ace Masahiro Tanaka.
Jose Altuve singled home another run in the seventh, off Yankees bullpen ace Dellin Betances, and the Houston Astros won 3-0 in the Bronx to set up the Divisional Series with the Royals.
Game one is Thursday at Kauffman Stadium.
Pitching on three days rest, Houston ace Dallas Keuchel shutout the Yankees for six innings. The Royals will only see him in game three of their best-of-five series. The Astros’ bullpen allowed just one walk in three innings.
Keuchel, a 20-game winner, held the Yankees to three hits and a walk.