Missouri, down six with just over five minutes to play, regrouped and pulled themselves to within one of Arkansas.
Wes Clark, at the free throw line with 3.3 seconds remaining in regulation, clanked both and the Razorbacks defeated the Tigers 61-60, Saturday at Mizzou Arena.
The loss was the Tigers fifth in a row in SEC play.
Teki Gill-Cesaer and Jonathan Williams III postgame
The Tigers used a 10-4 run to close out the first half for a 34-30 lead. Arkansas answered right out of the gate in the second, going on a 11-3 run to go up 41-37 with 16:59 to play.
Teki Gill-Cesaer hit a three pointer with 2:43 to play to tie it at 58-58, and hit another three to put Mizzou up 60-59 with under two minutes to play. Rashad Maddon answered with a jumper with 1:27 to play and the Tigers could grab the lead.
Gill-Caesar scored 16 points to lead Missouri (7-12, 1-5), and Johnathan Williams III added 15 points and grabbed 10 rebounds while Keith Shamburger chipped in 10 points.