St. Louis Rams quarterback Sam Bradford throws the fooball under pressure from the San Francisco 49ers in the fourth quarter at the Edward Jones Dome in St. Louis on December 26, 2010. The throw was good for a touchdown as St. Louis won the game 25-17. UPI/Bill Greenblatt

Bradford, the No. 1 pick of the draft, edned a three game stretch of no touchdown passes and five interceptions. He was 28 for 37 for 292 yards with no interceptions as the Rams beat San Francisco 25-17. Bradford has 335 completions, edging Peyton Manning’s record of 326 in 1998.

The Rams scored on their first drive for only the second time, after an interference call on the 49ers Nate Clements, with Steven Jackson scoring from the 1 on the next play.

Josh Brown kicked three field goals for St. Louis and has matched his career season best with 31. The 49ers led 14-12 at the half even though they only totaled three first downs and 82 yards in penalties. Their first score came on a Ted Ginn punt return, after the Rams went up 9-0 late in the first quarter on a safety and touchdown from Steven Jackson.

Former Missouri Tiger Danario Alexander had his best game as a pro with six catches for 99 yards including a 46 yarder than nearly turned into a touchdown. Alexander fell along the sideline after the long catch and got up after no 49er touched him while on the ground, but Alexander’s heel landed out of bounds just has he was back pedaling in the end zone. The Rams scored on their next play on a pass from Bradford to Laurent Robinson.