Jose Guillen went 2 for 4 and drove in three runs as the Royals beat the White Sox, 5-3, adn gave new manager Ned Yost his first series win.

The White Sox got on the board first on an Alex Rios home run off starter Brian Bannister in the second inning. The Sox then came up with three straight hits. On Alexei Ramirez’s single, it scored Mark Kotsay, but Mitch Maier gunned down Sox catcher AJ Pierzynski at third. Then Jason Kendall caught Ramirez trying to swipe second and just like the threat was over with the Royals down only 2-0.

The Royals went ahead, 3-2, in the fourth when they opened the inning with four straight singles against Gavin Floyd. The first was Mike Aviles’ pop fly which dropped between three fielders in short left field. David DeJesus singled, and Billy Butler and Guillen followed with RBI hits. Guillen added a two-run single in the fifth inning, a two-out hit with the bases loaded, for a 5-2 lead.

Bannister made it unfazed into the seventh, when Rios led off with a hit. Dusty Hughes allowed a run scoring single by Ramirez and the Sox never threatened after that.

The Royals finish 3-3 on the homestand and will head to Baltimore and Cleveland where they’ll play two games each.