The two busiest firehouses in Missouri are, not surprisingly, in our two biggest cities. But the numbers behind them might surprise a few people. The busiest firehouse in the state Is Engine Company 28 in St. Louis, which answered 3,337 calls last year, an average of more than nine calls every day. The second busiest firehouse is the one that houses Pumper unit 17 in Kansas City, which responded to 3,276 calls.